Yes, Vidalista 40 (which contains tadalafil) can be taken with or without food. However, taking it with a heavy or high-fat meal may delay the onset of action compared to taking it on an empty stomach. It is generally recommended to take Vidalista 40 about 30 minutes to 1 hour before anticipated sexual activity, regardless of food intake, for optimal effectiveness. If you have specific concerns or questions about taking Vidalista 40 with food, consult your healthcare provider for personalized advice.